陈美美,金煜峰,柴敏茵.1例肾移植术后颅内曲霉菌感染患儿的护理[J].上海护理,2020,20(S1):
1例肾移植术后颅内曲霉菌感染患儿的护理
Nursing experience sharing of one child with intracranial aspergillus infection after kidney transplantation
DOI:
中文关键词:  肾移植、颅内真菌感染、护理
英文关键词:
基金项目:
作者单位E-mail
陈美美 复旦大学附属华山医院 276977243@qq.com 
金煜峰* 复旦大学附属华山医院 kin.yufeng@fox.com 
柴敏茵 复旦大学附属华山医院  
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中文摘要:
      中枢神经系统真菌感染多发生于重症颅脑外伤、人类免疫缺陷病毒、器官移植后长期免疫抑制的人群,其中曲霉菌感染发生占神经系统真菌感染的5%~10%,病死率达90%。现报道1例我院于2019年5月收治的肾移植术后颅内曲霉菌感染患儿。严密的病情监测、精确的两性霉素B脂质体药物浓度配置,脑室内及静脉联合用药,同时做好抗排斥药物血药浓度监测、保护性隔离严密抗感染,积极处理并发症减少肾功能损伤以取得平衡是该例患儿治疗成功的关键。
英文摘要:
      Fungal infections of the central nervous system mostly occur in people with severe craniocerebral trauma, human immunodeficiency virus infection, and long-term immunosuppression after organ transplantation. Aspergillus infections account for 5% to 10% of fungal infections of the nervous system, and the mortality is 90%. One case of intracranial Aspergillus infection after renal transplantation in our hospital in May 2019 is reported. There are some points leads to good prognosis, such as Strict disease monitoring, accurate amphotericin B liposome drug concentration configuration, combined intraventricular and intravenous administration, good blood concentration monitoring of anti-rejection drugs, protective isolation and strict anti-infection, actively deal with complications and reduce renal function Injury
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