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吴敏,赵新鲜.14例乌司奴单抗治疗克罗恩病的疗效观察与护理体会[J].上海护理,2021,21(S1):
14例乌司奴单抗治疗克罗恩病的疗效观察与护理体会
Clinical observation and nursing experience of 14 patients with Crohn's disease treated with Ulinimumab
DOI：
中文关键词:  乌司奴单抗  克罗恩病  不良事件  护理体会
英文关键词:Ulinimumab  Crohn's disease  Adverse event  Nursing experience
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作者单位E-mail
吴敏 上海交通大学医学院附属仁济医院消化科 391349875@qq.com 
赵新鲜* 上海交通大学医学院附属仁济医院消化科 zhaoxinxian@renji.com 
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中文摘要:
      目的 总结乌司奴单抗在克罗恩病患者治疗中的护理体会。方法 回顾2020年5月至今我科接收乌司奴单抗治疗的14例克罗恩病患者资料,分析患者的一般资料、用药前后的疾病进展及不良事件的发生情况。结果 14例患者中,8例为首次注射乌司奴单抗,另6例为再次注射；其中,12例患者注射乌司奴单抗后症状明显好转出院。2例患者出现不良事件,均为腹痛、便血等胃肠道症状,最终因效果不理想、不良事件较重,改用其他药物治疗。结论 乌司奴单抗在治疗传统药物或生物制剂效果不佳的活动性克罗恩病患者中有着诸多优势,但在临床使用过程中,护理人员需密切关注可能出现的不良事件,并予以及时的对症处理。
英文摘要:
      Objective Summarizing the nursing experience of Ulinimumab in the treatment of Crohn's disease. Methods The clinical data of 14 patients with Crohn's disease treated with Ulinuzumab in our department from May 2020 to now were reviewed. The general information, disease progression before and after treatment and the occurrence of adverse events were analyzed. Results Among the 14 patients, 8 patients were injected with Ulinimumab for the first time, and the other 6 patients were reinjected; among them, 12 patients were discharged after the injection of Ulinimumab. Two patients had adverse events, including abdominal pain, hematochezia and other gastrointestinal symptoms. Conclusion Ulinuzumab has many advantages in the treatment of active Crohn's disease patients with poor effect of traditional drugs or biological agents, but in the process of clinical use, nurses need to pay close attention to the possible adverse events, and give timely symptomatic treatment.
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