| 侯睿.癌症患者放射性直肠炎预防和管理的最佳证据总结[J].上海护理,2022,22(4): |
| 癌症患者放射性直肠炎预防和管理的最佳证据总结 |
| Best evidence summary for prevention and management of radiation proctitis in cancer patients |
| DOI： |
| 中文关键词: 癌症患者 放射性直肠炎 预防 管理 循证护理 |
| 英文关键词:Cancer Patients Radiation Proctitis Prevention Management Evidence-Based Nursing |
| 基金项目:河南省医学科技攻关计划联合共建项目 |
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| 中文摘要: |
| 目的 检索、评价并整合国内外关于癌症患者放射性直肠炎预防和管理的相关证据,并对最佳证据进行总结。方法 系统检索BMJ Best Practice、UpToDate、Joanna Briggs Institute(JBI)循证卫生保健中心数据库、国际指南协作网、美国国家指南库、英国国家卫生与临床优化研究所、苏格兰校际指南网、加拿大安大略注册护士协会网、中国临床指南文库、Cochrane Library、PubMed、美国国家综合癌症网络、万方数据库、中国知网数据库、维普中文科技期刊全文数据库、中国生物医学文献数据库中所有关于放射性直肠炎预防和管理的证据,包括指南、专家共识、最佳实践、系统评价和证据总结。检索时限为2010年1月起至2020年7月。采用澳大利亚JBI循证卫生保健中心的文献评价标准和证据分级系统,对研究进行文献质量评价及证据级别评定。结果 共纳入15篇文献,其中指南2篇,专家共识3篇,临床决策2篇,系统评价8篇,总结了39条放射性直肠炎预防与管理的证据,包括诊断与评估、预防、药物治疗、非药物治疗、手术治疗、营养治疗、中医治疗和调护8个方面。结论 癌症患者放射性直肠炎预防与管理的最佳证据内容丰富,在应用时需要结合医院特点和临床环境,有针对性地选择最佳证据,部分证据仍有待更高质量的研究。 |
| 英文摘要: |
| Objective To retrieve, evaluate and integrate the relevant evidence of prevention and management of radiation proctitis in cancer patients at home and abroad, and to summarize the best evidence. Methods We systematically searched for evidence on prevention and management of radiation proctitis in BMJ, UpToDate, JBI, GIN, NGC, NICE, SIGN, RNAO, CGC,Cochrane Library, PubMed, NCCN, Wanfang, CNKI, CBM, including guidelines, expert consensus, best practice, systematic review and evidence summary. The retrieval period was from January 2010 to July 2020. The JBI evidence appraisal and recommendation system was used to evaluate the quality of studies and the level of evidence. Results A total of 15 articles were included, including 2 guidelines, 3 expert consensus, 2 clinical decision-making, and 8 systematic reviews, totally 39 pieces of evidence for the prevention and management of radiation proctitis were summarized, including 8 aspects of diagnosis and evaluation, prevention, drug treatment, non-drug treatment, surgical treatment, nutritional treatment, traditional Chinese medicine treatment and nursing care. Conclusions The best evidence for the prevention and management of radiation proctitis in cancer patients is rich in content. The application needs to combine the characteristics of the hospital and the clinical environment to select the best evidence in a targeted manner. Some of the evidence still needs higher quality research. |
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