| 许宝玲,吕倩,朱方方,苏虹虹,孔悦.结直肠癌患者术后早期经口进食时机的Meta分析[J].上海护理,2023,23(1): |
| 结直肠癌患者术后早期经口进食时机的Meta分析 |
| Early postoperative oral feeding timing in patients with colorectal cancer: a meta-analysis |
| DOI： |
| 中文关键词: 结直肠癌 早期经口进食 随机对照试验 Meta分析 |
| 英文关键词: |
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| 中文摘要: |
| 目的 分析术后早期进食对结直肠癌患者预后和并发症的影响,寻找术后早期进食的最佳时机。方法 计算机检索CNKI、Wan Fang Data、VIP、CBM、PubMed、Web of Science、Embase、The Cochrane Library数据库,检索从建库至2021-12之前发表的文献。采用RevMan5.4软件进行Meta分析。结果 共12篇文献纳入Meta分析。结果显示, 早期经口进食组术后首次排气时间较短(MD=-16.12h,95%CI：-19.32～-12.92h,P=0.00)；亚组分析显示：6～12h进食组、12h～24h进食组术后首次排气时间均短于传统经口进食组(MD分别为-16.12h、-24.82)。在术后总并发症发生率方面, 早期经口进食组总并发症发生率低于传统经口进食组(OR=0.52,95%CI：0.35～0.78,P=0.002)；亚组分析显示：6～12h进食组术后总并发症发生率低于传统经口进食组(OR=0.46)、12h～24h进食组与传统经口进食组术后总并发症发生率间差异无统计学意义(OR=0.61)。结论 结直肠癌术后患者早期进食的最佳时机可能为6h～12h,但尚需更多高质量的临床试验进一步研究。 |
| 英文摘要: |
| Objective To analyze the effects of early postoperative eating on the prognosis and complications of colorectal cancer patients, and to find the best timing for early postoperative eating. Methods CNKI, Wan Fang Data, VIP, CBM, PubMed, Web of Science, Embase, The Cochrane Library database were searched by computer, and the literatures published from the establishment of the library to 2021-12 were retrieved. Meta-analysis was performed using RevMan5.4 software. Results A total of 12 articles were included in the meta-analysis. The results showed that the early oral feeding group had a shorter first gassing time after surgery (MD=-16.12h, 95%CI: -19.32--12.92h, P=0.00); subgroup analysis showed that: 6-12h feeding group, The 12h-24h feeding group had shorter time to first gassing after operation than the traditional oral feeding group (MD were -16.12h, -24.82, respectively). In terms of the total postoperative complication rate, the total complication rate in the early oral feeding group was lower than that in the traditional oral feeding group (OR=0.52, 95%CI: 0.35-0.78, P=0.002); subgroup analysis showed: The postoperative total complication rate in the 6-12h feeding group was lower than that in the traditional oral feeding group (OR=0.46), and there was no significant difference in the postoperative total complication rates between the 12-24 h feeding group and the traditional oral feeding group ( OR=0.61). Conclusions The best time to eat early in patients with colorectal cancer after surgery may be 6 to 12 hours, but more high-quality clinical trials are needed for further study. |
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