| 章晓云,邓俊黎,张霓,王静,颜瑾,叶婷.营养风险筛查联合个性化营养方案对失代偿乙肝肝硬化患者营养状况的影响[J].上海护理,2019,19(4): |
| 营养风险筛查联合个性化营养方案对失代偿乙肝肝硬化患者营养状况的影响 |
| The effect of nutritional risk screening combined with individualized nutrition program on the nutritional status of patients with decompensated hepatitis B cirrhosis |
| DOI： |
| 中文关键词: 营养风险 筛查 个性化 营养方案 失代偿乙肝肝硬化 营养状况 |
| 英文关键词:nutritional risk screening individualization nutrition program decompensated hepatitis B liver cirrhosis nutritional status |
| 基金项目:湖北省自然科学基金计划面上项目（编号：2016CFB683） |
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| 中文摘要: |
| 目的：探讨营养风险筛查联合个性化营养方案对失代偿乙肝肝硬化（DHBLC）患者营养状况的影响。方法：选取2016年1月至2016年12月本院收治的DHBLC患者80例，依据随机数字表法分为营养组和常规组，每组40例，常规组给予常规治疗，营养组在此基础上给予营养风险筛查联合个性化营养方案治疗，随访3个月后，比较两组人体营养参数[体质量指数（BMI）、三角肌皱襞厚度（TSF）、上臂肌围（MAMC）]、机体营养参数[血白蛋白（ALB）、前白蛋白（PALB）、球蛋白前体（Pre ALB）、氮平衡]、肝功能[丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）、总胆红素（TBIL）]、改良主管全面评价法（SGA）分级。结果：营养组和常规组治疗3个月后BMI、TSF、MAMC、ALB、PALB、Pre ALB、氮平衡明显高于治疗前，营养组治疗3个月后BMI、TSF、MAMC、ALB、PALB、Pre ALB、氮平衡明显高于常规组，差异有统计学意义（P<0.05）；营养组和常规组治疗3个月后ALT、AST、TBIL、SGA分级明显低于治疗前，营养组治疗后ALT、AST、TBIL、SGA分级明显低于常规组，差异有统计学意义（P<0.05）。结论：营养风险筛查联合个性化营养方案可有效改善DHBLC患者营养不良状态，有利于改善患者的肝功能，值得临床作进一步推广。 |
| 英文摘要: |
| Objective:To discuss the effect of nutritional risk screening combined with individualized nutrition program on the nutritional status of patients with decompensated hepatitis B cirrhosis (DHBLC).Methods: 80 patients with DHBLC were selected from January 2016 and December 2016 in our Hospital,according to the random distribution, all patients were divided into nutrition group (40 cases)and control group(40 cases),control group was treated with routine treatment,nutrition group on the basis was treated with nutritional risk screening combined with individualized nutrition program.Comparison of two groups of human nutrition parameters [body mass index (BMI), (TSF), the thickness of the deltoid fold arm muscle circumference (MAMC), nutritional parameters [serum albumin (ALB), prealbumin (PALB), globulin precursor (Pre ALB), nitrogen balance, liver function [alanine aminotransferase the enzyme (ALT) and aspartate aminotransferase (AST), total bilirubin (TBIL), improved the competent comprehensive evaluation method (SGA) classification.Results:The after treatmen of BMI,TSF,MAMC,ALB,PALB,Pre ALB and nitrogen balance of nutrition group and control group were significantly higher than that before treatment,the after treatmen of BMI,TSF,MAMC,ALB,PALB,Pre ALB and nitrogen balance of nutrition group was significantly higher than that control group.The after treatmen of ALT,AST,TBIL,SGA classification of nutrition group and control group were significantly lower than that before treatment,the after treatmen of ALT,AST,TBIL,SGA classification of nutrition group was significantly lower than that control group.Conclusions:Nutritional risk screening combined with personalized nutrition program can effectively improve the malnutrition status of DHBLC patients.It is beneficial to improve the liver function of the patients,it’s worth for further clinical promotion. |
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